Longitudinal axons are guided by Slit/Robo signals from the floor plate
نویسندگان
چکیده
منابع مشابه
Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals.
Longitudinal axons transmit all signals between the brain and spinal cord. Their axon tracts through the brain stem are established by a simple set of pioneer axons with precise trajectories parallel to the floor plate. To identify longitudinal guidance mechanisms in vivo, the overall role of floor plate tissue and the specific roles of Slit/Robo signals were tested. Ectopic induction or geneti...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2010
ISSN: 1933-6918,1933-6926
DOI: 10.4161/cam.4.3.11219